(6, 7, 8, 9) Ozone has been used with good results in the treatment of patients with diabetic foot, because of its germicidal properties and its influence on the processes of oxygen metabolism, and other effects. (5) Ozone can exert protective effects by oxidative preconditioning, stimulating and/or preserving the endogenous antioxidant systems and by blocking the xanthine / xanthine oxidase pathway for reactive oxygen species generation, as demonstrated in studies of the damage induced by carbotetrachloride (CCL4) or by hepatic and renal ischemia-reperfusion.

(2, 3, 4) Ozone (O3) is a strong antioxidant. Therapy is given in special therapeutic chambers, which were earlier used primarily to treat illnesses of deep sea divers.

Hyperbaric oxygen therapy (HBOT) is a form of treatment in which a patient breathes 100% oxygen at higher than normal atmospheric pressure that is greater than 1 atmosphere absolute (ATA). (1) Hyperbaric Medicine is the fascinating use of barometric pressure for delivering increased oxygen dissolved in plasma to body tissues.

There are many approaches to management, with large variations in practice at local and international levels. After healing, recurrence rates are high. Leg ulceration is chronic, and an ulcer may be present for months or years without healing. Other disease processes may also be involved, such as diabetes or rheumatoid disease. Venous disease is present in the majority of cases peripheral vascular disease may coexist or may be the main cause of an ulcer. Leg ulcers are more common in women than men, and the prevalence increases with age. Adjuvant HBO and Ozone Therapy showed effective adjunctive therapy and we recommend a Randomized Controlled Trial to prove that effect.Ĥ–Introduction Leg ulcers are a common problem thought to affect about 1% of the population at some point in their lives and about 1.

HBO and Ozone Therapy increased the healing rate of these ulcers, and avoided amputation. pp.44-53, 2011 Editado por AEPROMO (Asociación Española de Profesionales Médicos en Ozonoterapia) Creative Commons: reconocimiento.ġ-Adjuvant Hyperbaric Oxigen and ozone therapy in the treatment of chonic leg and foot ulcers (pilot clinical study).Ģ-Hyperbaric oxygen therapy Ozone therapy Leg ulcers Foot ulcers.ģ-Abstract This pilot study describes the clinical effects of Adjunctive Hyperbaric Oxygen Therapy (HBOT) and Ozone Therapy in the treatment of chronic ulcers most of which did not respond to standard wound care and conventional methods of therapy and the patients were threatened by amputation.

Gatos queratitis ocular